When it comes to over-the-counter pain relievers, two of the most popular choices are Ibuprofen and Aleve. Both medications are nonsteroidal anti-inflammatory drugs (NSAIDs) that help reduce pain, inflammation, and fever.
While they serve similar purposes, they have distinct differences that can affect your choice depending on your needs. In this guide, we’ll compare Ibuprofen and Aleve in terms of their effectiveness, duration of action, side effects, and usage considerations.
What is Aleve?
Aleve is a brand name for naproxen, another NSAID. Like ibuprofen, it works by blocking the production of prostaglandins. However, Aleve has a longer duration of action compared to ibuprofen, which makes it ideal for people who need relief from chronic conditions.
Key Uses of Aleve:
- Pain relief (arthritis, muscle pain, back pain, etc.)
- Reducing inflammation
- Relieving menstrual cramps
Ibuprofen vs Aleve: Duration of Action
One of the key differences between ibuprofen and Aleve is how long they last in the body. Ibuprofen typically provides pain relief for 4-6 hours, while Aleve offers longer-lasting relief, lasting 8-12 hours. This means that Aleve may be more convenient for those who need less frequent dosing.
Medication | Duration of Action |
---|---|
Ibuprofen | 4-6 hours |
Aleve | 8-12 hours |
Dosage and Frequency
- Ibuprofen: The typical adult dosage is 200-400 mg every 4-6 hours, with a maximum daily dose of 1200 mg (unless directed otherwise by a healthcare provider).
- Aleve: For adults, the recommended dose is 220 mg every 8-12 hours, with a maximum daily dose of 660 mg.

Side Effects
Both Ibuprofen and Aleve come with potential side effects, especially if used for extended periods or in high doses. These can include:
- Upset stomach or gastrointestinal issues
- Kidney problems (especially with prolonged use)
- Increased risk of heart attack or stroke with long-term use
However, since Aleve has a longer duration of action, it may cause more pronounced gastrointestinal issues when taken regularly. It is essential to follow the recommended dosage to minimize these risks.
Which One Should You Choose?
Choosing between Ibuprofen and Aleve depends on your specific needs:
- Short-term pain relief: Ibuprofen may be the better option for temporary discomfort, as it is fast-acting and available in various forms (tablets, liquid gels, etc.).
- Chronic pain relief: Aleve is often recommended for individuals with conditions requiring longer-lasting pain relief, such as arthritis, due to its extended duration of action.
- Frequency of use: If you need to take pain relievers multiple times a day, Aleve might be more convenient, as it only needs to be taken every 8-12 hours.
Both Ibuprofen and Aleve are effective NSAIDs that can relieve pain and inflammation. However, their differences in duration of action, dosing schedule, and potential side effects make them suitable for different types of pain management. It’s essential to consider the type and frequency of pain you’re experiencing when choosing between these medications.
By understanding the differences between ibuprofen and Aleve, you can make an informed decision about which pain reliever is right for you.